This diagnostic procedure measures the amount of hydrogen in exhaled breath after ingestion of a lactulose solution. Elevated hydrogen levels indicate bacterial fermentation of the lactulose in the colon, providing insights into conditions such as small intestinal bacterial overgrowth (SIBO) and carbohydrate malabsorption. A typical test involves baseline breath samples followed by additional samples at regular intervals after lactulose consumption. The resulting data, presented as a graph of hydrogen concentration over time, allows healthcare professionals to assess the timing and magnitude of hydrogen production.
Offering a non-invasive method for evaluating gastrointestinal function, this test aids in diagnosing conditions that can cause significant discomfort and nutritional deficiencies. Its development provided a more comfortable alternative to invasive procedures previously used to assess similar conditions. It provides valuable data for personalized treatment plans and ongoing monitoring of treatment efficacy.